Title: What are the Western medicines for treating lung cancer
In recent years, the incidence of lung cancer has increased year by year, becoming one of the major diseases that threaten human health worldwide. With the advancement of medical technology, the types of Western medicines for treating lung cancer are becoming increasingly abundant. This article will combine popular topics and hot topics across the network for the past 10 days to introduce the Western medicine and its mechanism of action to everyone in detail to help patients and their families better understand the relevant treatment options.
1. Current status and treatment challenges of lung cancer
Lung cancer is one of the most common malignant tumors in the world, and according to the World Health Organization (WHO), the incidence and mortality of lung cancer are among the top. Although advances in early diagnosis and treatment technologies have brought hope to patients, the treatment of advanced lung cancer still faces great challenges. Western medicine treatment is one of the important means of comprehensive treatment of lung cancer, mainly including chemotherapy drugs, targeted drugs and immunotherapy drugs.
2. Classification of Western medicines for treating lung cancer
Western medicines for treating lung cancer can be divided into the following categories according to their mechanism of action:
Drug Category | Representative medicine | Mechanism of action | Applicable groups |
---|---|---|---|
Chemotherapy drugs | Cisplatin, carboplatin, pemetrexed | Kill cancer cells by inhibiting the synthesis of tumor cells' DNA or destroying cell structures | Widely used in non-small cell lung cancer and small cell lung cancer |
Targeted drugs | Gefitinib, erlotinib, osimertinib | Inhibit tumor growth by targeting specific gene mutations (such as EGFR, ALK) | Patients with non-small cell lung cancer with EGFR or ALK gene mutations |
Immunotherapy drugs | Pembrolizumab, Nivolumab | Attacking tumor cells by activating the patient's autoimmune system | Patients with high PD-L1 expression or high microsatellite instability |
3. Detailed explanation of popular treatment drugs
1.Chemotherapy drugs
Chemotherapy drugs are one of the cornerstones of lung cancer treatment. Especially for patients with advanced lung cancer, chemotherapy can significantly prolong survival and improve quality of life. Cisplatin and carboplatin are commonly used platinum chemotherapy drugs and are often used in combination with other drugs. Pemetrexed is a new anti-metabolic drug suitable for the treatment of non-small cell lung cancer.
2.Targeted drugs
Targeted drugs have attracted much attention for their precise therapeutic effects and low side effects. Osimirtinib is a third-generation EGFR inhibitor and has significant efficacy in patients with positive EGFR T790M mutations. In addition, crizotinib and aletinib targeting ALK gene mutations also provide patients with more options.
3.Immunotherapy drugs
Immunotherapy is an important breakthrough in the treatment of lung cancer in recent years. Pembolizumab (Keytruda) and nivolumab (Opdivo) activate the immune system to attack tumor cells by blocking the PD-1/PD-L1 pathway. This type of drug is especially suitable for patients with high PD-L1 expression, and some patients can even achieve long-term survival.
4. Selection and precautions for therapeutic drugs
Choosing suitable lung cancer treatment drugs requires comprehensive consideration of the patient's pathological type, genetic test results, physical condition and economic factors. Here are some precautions:
5. Future Outlook
With the rapid development of precision medicine and immunotherapy, the prospects for treatment of lung cancer are becoming brighter. New drugs such as bispecific antibodies and CAR-T cell therapy are showing great potential in clinical trials. In the future, individualized treatment and multidisciplinary collaboration will become the mainstream direction of lung cancer treatment.
In short, there are many types of Western medicines for treating lung cancer, and patients should choose the treatment plan that is most suitable for them under the guidance of professional doctors. I hope this article can provide valuable reference information for patients and families.
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